In the treacherous frontier city of Samurai Town, a ruthless bank robber is sprung from jail by wealthy warlord The Governor, whose adopted granddaughter Bernice has gone missing. The Governor offers the prisoner his freedom in exchange for retrieving the runaway. Strapped into a leather suit that will self-destruct within five days, the bandit sets off on a journey to find the young womanâ€”and his own path to redemption.
Ray Tango and Gabriel Cash are narcotics detectives who, while both being extremely successful, can\'t stand each other. Crime Lord Yves Perret, furious at the loss of income that Tango and Cash have caused him, frames the two for murder. Caught with the murder weapon on the scene of the crime, the two have no alibi. Thrown into prison with most of the criminals they helped convict, it appears that they are going to have to trust each other if they are to clear their names and catch the evil Perret.